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Week 1 fantasy football rankings: Time to set your lineup

by September 3, 2025
by September 3, 2025

The wait is finally over. Week 1 of the 2025 NFL season is at hand.

As important as it is for NFL teams to get off to a strong start, it’s even more critical for fantasy football teams to do so – since our playoffs start a month earlier than theirs.

As usual, there are great matchups for the prime-time games, with the two top-rated fantasy quarterbacks going head-to-head on Sunday night as Josh Allen and the Buffalo Bills host Lamar Jackson and the Baltimore Ravens.

Another intriguing story line is how big an impact new head coach Ben Johnson will have on the Chicago Bears … and how much his absence will affect the Detroit Lions offense.

Let’s get to the rankings! (*-double-check status before kickoff)

Week 1 fantasy football QB rankings

  • Rams coach Sean McVay says Matthew Stafford (back) will start vs. the Texans
  • Cowboys QB Dak Prescott may be under even more pressure following Micah Parsons trade

Week 1 fantasy football RB rankings

  • De’Von Achane (calf) ‘remains on track’ to play in the Dolphins opener at the Colts
  • Tony Pollard gets an early-season boost with top backup Tyjae Spears on injured reserve
  • With Joe Mixon out for at least four games, Nick Chubb appears to be in line to start for the Texans

Week 1 fantasy football WR rankings

  • Niners wideout Jauan Jennings (calf) returned to practice Monday
  • Tyreek Hill (oblique) missed three weeks of practice but has returned to the field
  • Jayden Reed revealed he has a small fracture in his foot, but he plans to play through it

Week 1 fantasy football TE rankings

Week 1 fantasy football K rankings

Week 1 fantasy football D/ST rankings

This post appeared first on USA TODAY
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