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MLS playoff predictions: Will Messi play for the Cup?

by November 29, 2025
by November 29, 2025

The road to MLS Cup 2025 has reached its final four.

Here’s what’s on tap:

  • Inter Miami vs. New York City FC — Saturday, Nov. 29 at 6 p.m. ET (Apple TV)
  • San Diego FC vs. Vancouver Whitecaps — Saturday, Nov. 29 at 9 p.m. ET (Apple TV)

In the Eastern Conference final, Lionel Messi and Inter Miami host the biggest underdog left in what has been a very chalk MLS Cup Playoffs, New York City FC. NYCFC — the conference’s No. 5 seed — has upset Charlotte FC and the Supporters’ Shield-winning Philadelphia Union en route to Saturday’s showdown in Fort Lauderdale, Florida. Messi and Miami would host MLS Cup on Saturday, Dec. 6 with a win. 

In the Western Conference final, San Diego FC is on a quest to complete the greatest expansion season in league history. Standing in their way on Saturday are the Vancouver Whitecaps. In their 15-season MLS existence, this is the furthest in the playoffs that the Whitecaps have progressed.

Here’s how USA TODAY Network soccer experts see how conference finals of the MLS playoffs will play out, including bonus picks for MLS Cup:

MLS playoff predictions, picks for conference finals

Inter Miami vs. New York City FC

  • Jim Reineking: Inter Miami
  • Jacob Shames: Inter Miami
  • Seth Vertelney: Inter Miami
  • James Weber: Inter Miami

San Diego FC vs. Vancouver Whitecaps

  • Jim Reineking: Vancouver Whitecaps
  • Jacob Shames: Vancouver Whitecaps
  • Seth Vertelney: San Diego FC
  • James Weber: San Diego FC

MLS Cup 2025

  • Jim Reineking: Inter Miami over Vancouver Whitecaps
  • Jacob Shames: Inter Miami over Vancouver Whitecaps
  • Seth Vertelney: Inter Miami over San Diego FC
  • James Weber: Inter Miami over San Diego FC

USA TODAY Sports’ 48-page special edition commemorates 30 years of Major League Soccer, from its best players to key milestones and championship dynasties to what exciting steps are next with the World Cup ahead. Order your copy today!

This post appeared first on USA TODAY
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