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NFL Week 18 odds and expert predictions for every matchup

by December 30, 2025
by December 30, 2025

The final week of the NFL regular season is upon us.

Almost all playoff spots have been clinched. The Tampa Bay Buccaneers host the Carolina Panthers in a battle for the NFC South title and the final playoff slot in the conference.

The Seattle Seahawks and San Francisco 49ers meet in the Bay Area for chance to get the No. 1 seed in the NFC.

The final game of the regular season features the Baltimore Ravens and Pittsburgh Steelers in a win-or-go home matchup.

Playoff positions and teams will be determined by the end of Jan. 4. The roadmap to Santa Clara will be set. USA TODAY Sports provides the early predictions for Week 18:

Odds courtesy of BetMGM.

NFL Week 18 predictions, picks

Carolina Panthers vs. Tampa Bay Buccaneers

Date: Saturday, Jan. 3

Time: 4:30 p.m. ET

Location: Raymond James Stadium, Tampa, FL

TV: ESPN

Streaming: FUBO

Spread: Bucs (-3)

Tyler Dragon, USA TODAY: Bucs 21, Panthers 17

A win-or-go-home game in Tampa Bay. The Bucs have lost four-straight games and don’t have the look of a playoff team. But can Bryce Young lift the Panthers in the biggest game of his NFL career? I think the Bucs hang on at home.

Seattle Seahawks vs. San Francisco 49ers

Date: Saturday, Jan. 3

Time: 8 p.m. ET

Location: Levi’s Stadium, Santa Clara, CA

TV: ESPN

Streaming: FUBO

Spread: 49ers (-1.5)

Tyler Dragon, USA TODAY: Seahawks 28, 49ers 25

The 49ers have overachieved all year despite major injuries on both sides of the ball. Seattle is the more balanced team, with a better defense. The Seahawks lost to San Francisco at home in Week 1. They return the favor in Santa Clara this week.

New Orleans Saints vs. Atlanta Falcons

Date: Sunday, Jan. 4

Time: 1 p.m. ET

Location: Mercedes-Benz Stadium, Atlanta

TV: FOX

Streaming: FUBO

Spread: Falcons (-2.5)

Tyler Dragon, USA TODAY: Falcons 25, Saints 21

Both teams are playing for bragging rights. The Saints have quietly won four straight games. Bijan Robinson and the Falcons score just enough to win in front of their home fans.

Cleveland Browns vs. Cincinnati Bengals

Date: Sunday, Jan. 4

Time: 1 p.m. ET

Location: Paycor Stadium, Cincinnati

TV: CBS

Streaming: FUBO

Spread: Bengals (-7.5)

Tyler Dragon, USA TODAY: Bengals 26, Browns 20

Myles Garrett’s pursuit of the sack record is the story of this game. I think he sets the record against a below-average Bengals O-line. However, the Bengals should win.

Green Bay Packers vs. Minnesota Vikings

Date: Sunday, Jan. 4

Time: 1 p.m. ET

Location: U.S. Bank Stadium, Minneapolis

TV: CBS

Streaming: FUBO

Spread: Vikings (-6.5)

Tyler Dragon, USA TODAY: Packers 24, Vikings 20

The Packers are locked in the No. 7 seed in the NFC and could rest multiple starters. But I still think Green Bay has enough to get the win.

Dallas Cowboys vs. New York Giants

Date: Sunday, Jan. 4

Time: 1 p.m. ET

Location: MetLife Stadium, East Rutherford, NJ

TV: FOX

Streaming: FUBO

Spread: Cowboys (-5)

Tyler Dragon, USA TODAY: Cowboys 26, Giants 20

Both these teams should be better next year. The Cowboys and their high-powered offense finish the season on a high note.  

Tennessee Titans vs. Jacksonville Jaguars

Date: Sunday, Jan. 4

Time: 1 p.m. ET

Location: EverBank Stadium, Jacksonville, FL

TV: FOX

Streaming: FUBO

Spread: Jaguars (-11.5)

Tyler Dragon, USA TODAY: Jaguars 27, Titans 20

The Jaguars are playing for playoff positioning. That’s bad news for an inferior Titans club. Cam Ward will make a couple plays that will have fans optimistic about the future.

Indianapolis Colts vs. Houston Texans

Date: Sunday, Jan. 4

Time: 1 p.m. ET

Location: NRG Stadium, Houston, TX

TV: CBS

Streaming: FUBO

Spread: Texans (-10)

Tyler Dragon, USA TODAY: Texans 26, Colts 17

The Texans are the hottest team in the NFL right now (as I said in a recent column). Houston extends its NFL-best win streak to nine games and enters the playoffs as a scary team.

New York Jets vs. Buffalo Bills  

Date: Sunday, Jan. 4

Time: 4:25 p.m. ET

Location: Highmark Stadium, Orchard Park, NY

TV: CBS

Streaming: FUBO

Spread: Bills (-8.5)

Tyler Dragon, USA TODAY: Bills 27, Jets 17

The Bills are coming off a tough loss to the defending Super Bowl champion Eagles. Expect Buffalo to win in its final game at Highmark Stadium. The Jets are thinking about the draft.

Detroit Lions vs. Chicago Bears

Date: Sunday, Jan. 4

Time: 4:25 p.m. ET

Location: Soldier Field, Chicago

TV: FOX

Streaming: FUBO

Spread: Bears (-2.5)

Tyler Dragon, USA TODAY: Bears 27, Lions 26

The Bears are the most improved team in the NFC. The Lions are the most disappointing team in the NFC. Fittingly, Chicago wins.

Los Angeles Chargers vs. Denver Broncos

Date: Sunday, Jan. 4

Time: 4:25 p.m. ET

Location: Empower Field at Mile High, Denver

TV: CBS

Streaming: FUBO

Spread: Broncos (-7.5)

Tyler Dragon, USA TODAY: Broncos 24, Chargers 20

The Chargers are undefeated in the AFC West this year. Los Angeles might rest multiple starters in Week 18. The Broncos need to win to clinch the No. 1 seed in the AFC. They’ll do it.

Kansas City Chiefs vs. Las Vegas Raiders

Date: Sunday, Jan. 4

Time: 4:25 p.m. ET

Location: Allegiant Stadium, Las Vegas

TV: CBS

Streaming: FUBO

Spread: Chiefs (-5.5)

Tyler Dragon, USA TODAY: Chiefs 24, Raiders 20

Tank for the No. 1 draft pick is alive and well in Las Vegas. The Raiders clinch the 2026 top pick with a loss. The Chiefs are motivated to play well in what seems to be Travis Kelce’s final game.

Arizona Cardinals vs. Los Angeles Rams

Date: Sunday, Jan. 4

Time: 4:25 p.m. ET

Location: SoFi Stadium, Inglewood, CA

TV: FOX

Streaming: FUBO

Spread: Rams (-9.5)

Tyler Dragon, USA TODAY: Rams 28, Cardinals 17

The Rams are playing for playoff positioning. The Cardinals are already thinking about how different their roster will look next year. Advantage Rams.

Miami Dolphins vs. New England Patriots

Date: Sunday, Jan. 4

Time: 4:25 p.m. ET

Location: Gillette Stadium, Foxborough, MA

TV: FOX

Streaming: FUBO

Spread: Patriots (-10.5)

Tyler Dragon, USA TODAY: Patriots 28, Dolphins 19

The AFC East Champion Patriots can still clinch the top seed in the AFC. Expect New England to dominate a Dolphins team ready for vacation in South Beach.

Washington Commanders vs. Philadelphia Eagles

Date: Sunday, Jan. 4

Time: 4:25 p.m. ET

Location: Lincoln Financial Field, Philadelphia

TV: CBS

Streaming: FUBO

Spread: Eagles (-8)

Tyler Dragon, USA TODAY: Eagles 24, Commanders 17

The Eagles have won three straight games and are beginning to resemble the team that won Super Bowl 59. The Jayden Daniels-less Commanders are ready for this season to end.

Baltimore Ravens vs. Pittsburgh Steelers

Date: Sunday, Jan. 4

Time: 8:20 p.m. ET

Location: Acrisure Stadium, Pittsburgh

TV: NBC

Streaming: Peacock

Spread: Ravens (-3.5)

Tyler Dragon, USA TODAY: Ravens 25, Steelers 20

Baltimore’s gameplan should center around handing Derrick Henry the football regardless of Lamar Jackson’s status. DK Metcalf’s suspension hinders Pittsburgh’s offense. The Ravens win in a winner-take-all game.

Follow USA TODAY Sports’ Tyler Dragon on X @TheTylerDragon.

Our team of savvy editors independently handpicks all recommendations. If you purchase through our links, the USA Today Network may earn a commission. Prices were accurate at the time of publication but may change.

This post appeared first on USA TODAY
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