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NFL Week 2 picks: Chiefs or Eagles in Super Bowl 59 rematch?

by September 12, 2025
by September 12, 2025

  • Week 2 will feature four prime-time games between Thursday and Monday, including an ‘MNF’ doubleheader.
  • The game of the week? Gotta be the Super Bowl 59 rematch between the Eagles and Chiefs in Kansas City.
  • Week 1 turned out to be highly unpredictable, but one of our experts went 11-5.

The NFL season largely returns to a more normal cadence in Week 2 after rolling out four prime-time games in five nights during kickoff weekend. OK, this weekend will also offer four prime-time games in five nights − but that’s due to a ‘Monday Night Football’ doubleheader, so you get to enjoy a football-free Friday … unless you’re miffed if you have to find something else to do on Friday night. (Sorry for you.)

Onward.

Speaking of prime time, Week 2 starts nicely with Prime Video’s first game of the season as the Washington Commanders visit the Green Bay Packers for their only scheduled matchup against former NFC East nemesis Micah Parsons.

Sunday night serves as a showcase for the Atlanta Falcons and Minnesota Vikings and their sophomore quarterbacks, Michael Penix Jr. and J.J. McCarthy, respectively. Monday’s twinbill offers a matchup of 2024 division winners (Buccaneers-Texans) and an AFC West showdown as the Los Angeles Chargers visit the Las Vegas Raiders in the nightcap.

But Week 2’s  entrée is a Sunday afternoon Super Bowl 59 rematch − the Kansas City Chiefs trying to notch their first win of the season against a Philadelphia Eagles squad that not only ended K.C.’s three-peat bid but issued the Chiefs a Super Sunday beatdown. Who wins a contest between teams that have actually met in two of the past three Super Bowls? USA TODAY’s panel of NFL experts weighs in.

(Odds provided by BetMGM)

This post appeared first on USA TODAY
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