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Former NFL Defensive Player of the Year out for season, per reports

by September 22, 2025
by September 22, 2025

The San Francisco 49ers can’t seem to shake persistent injuries amid the team’s 3-0 start. On Monday, the team learned of its mostly costly personnel loss yet.

Defensive end Nick Bosa suffered a torn anterior cruciate ligament in Sunday’s 16-15 win against the Arizona Cardinals and will miss the rest of the season, according to multiple reports.

Bosa exited the game late in the first quarter after being knocked to the ground on a pass rush. He gave a thumbs down as he headed to the locker room and did not return to the game.

Bosa previously suffered a torn ACL in Week 2 of the 2020 season. He returned the following year to earn his second of five career Pro Bowl berths, and he was named the NFL’s Defensive Player of the Year in 2022.

The 49ers already have suffered significant injury hits to quarterback Brock Purdy, who missed his second consecutive start Sunday while dealing with shoulder and toe injuries, as well as tight end George Kittle, who landed on injured reserve with a hamstring injury suffered in Week 1. Wide receiver Jauan Jennings also sat out Sunday due to shoulder and ankle injuries.

This post appeared first on USA TODAY
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